Protein Name UDP-glucose 4-epimerase
Organism Caenorhabditis elegans
Gene ID 173171
Gene Symbol

gale-1

UniProt Q564Q1 (GALE_CAEEL)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 1
Description

UDP-glucose 4-epimerase

Gene Summary

Enables UDP-N-acetylglucosamine 4-epimerase activity and UDP-glucose 4-epimerase activity. Involved in several processes, including gonad morphogenesis; negative regulation of endoplasmic reticulum unfolded protein response; and positive regulation of vulval development. Predicted to be active in cytosol. Is expressed in head; hypodermis; intestine; nervous system; and reproductive system. Used to study galactosemia. Human ortholog(s) of this gene implicated in galactose epimerase deficiency and thrombocytopenia. Orthologous to human GALE (UDP-galactose-4-epimerase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • UDP-glucose 4-epimerase
  • CELE_C47B2.6
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Properties