| Protein Name | Na(+)/H(+) exchanger protein 2 |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 174242 |
| Gene Symbol | nhx-2 |
| UniProt | Q8T5S1 (NHX2_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
2
Total Number of Articles : 2 |
Description |
Na(+)/H(+) exchanger protein 2 |
| Gene Summary |
Enables sodium:proton antiporter activity. Involved in several processes, including determination of adult lifespan; positive regulation of growth rate; and regulation of nematode pharyngeal pumping. Located in apical plasma membrane. Is expressed in intestine. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 19; congenital secretory sodium diarrhea 8; congestive heart failure; and end stage renal disease. Orthologous to several human genes including SLC9A3 (solute carrier family 9 member A3) and SLC9A5 (solute carrier family 9 member A5). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |