| Protein Name | gamma-aminobutyric acid type B receptor subunit 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 54393 |
| Gene Symbol | Gabbr1 |
| UniProt | Q9WV18 (GABR1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
44
Total Number of Articles : 57 |
Description |
gamma-aminobutyric acid type B receptor subunit 1 |
| Gene Summary |
Enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within gamma-aminobutyric acid signaling pathway. Located in cytoplasm; postsynaptic membrane; and presynaptic membrane. Part of G protein-coupled receptor dimeric complex. Is active in GABA-ergic synapse and Schaffer collateral - CA1 synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in alcohol dependence; amphetamine abuse; cocaine dependence; heroin dependence; and nicotine dependence. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |