Protein Name epithelial cell adhesion molecule
Organism Homo sapiens
Gene ID 4072
Gene Symbol


UniProt P16422 (EPCAM_HUMAN)
Relationships Total Number of functionally related compound(s) : 354
Total Number of Articles : 398

epithelial cell adhesion molecule

Gene Summary

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

  • epithelial cell adhesion molecule
  • adenocarcinoma-associated antigen
  • cell surface glycoprotein Trop-1
Click to show/hide the synonyms