| Protein Name | epithelial cell adhesion molecule |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4072 |
| Gene Symbol | EPCAM |
| UniProt | P16422 (EPCAM_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
354
Total Number of Articles : 398 |
Description |
epithelial cell adhesion molecule |
| Gene Summary |
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] |
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| Properties | |