Protein Name RAD21 cohesin complex component a
Organism Danio rerio
Gene ID 322275
Gene Symbol

rad21a

UniProt Q6TEL1 (RA21A_DANRE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 1
Description

RAD21 cohesin complex component a

Gene Summary

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including chordate embryonic development; enteric nervous system development; and heart development. Predicted to be located in several cellular components, including chromosome, centromeric region; nuclear matrix; and spindle pole. Predicted to be part of cohesin complex. Is expressed in several structures, including brain; digestive system; head; optic cup; and ventricular zone. Used to study Cornelia de Lange syndrome; brain cancer; and congenital heart disease. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; endometrial cancer; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • double-strand-break repair protein rad21 homolog A
  • RAD21 homolog a
  • SCC1 homolog
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Properties