Protein Name DNA (cytosine-5-)-methyltransferase 3 alpha b
Organism Danio rerio
Gene ID 553189
Gene Symbol

dnmt3ab

UniProt F1R1K5 (F1R1K5_DANRE), B3DGZ8 (B3DGZ8_DANRE), Q588C4 (Q588C4_DANRE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

DNA (cytosine-5-)-methyltransferase 3 alpha b

Gene Summary

Predicted to enable DNA (cytosine-5-)-methyltransferase activity; DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within DNA methylation and regulation of gene expression. Predicted to be located in nucleus. Is expressed in several structures, including auditory capsule; digestive system; eye; pleuroperitoneal region; and spinal cord neural tube. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndrome; and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • DNA (cytosine-5)-methyltransferase 3A
  • DNA (cytosine-5-)-methyltransferase 6
  • dnmt3a1
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Properties