| Protein Name | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4245 |
| Gene Symbol | MGAT1 |
| UniProt | P26572 (MGAT1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
110
Total Number of Articles : 103 |
Description |
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
| Gene Summary |
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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