Protein Name secreted protein, acidic, cysteine-rich (osteonectin)
Organism Danio rerio
Gene ID 321357
Gene Symbol

sparc

UniProt Q6IQH0 (Q6IQH0_DANRE)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 2
Description

secreted protein, acidic, cysteine-rich (osteonectin)

Gene Summary

Predicted to enable calcium ion binding activity; collagen binding activity; and extracellular matrix binding activity. Acts upstream of or within several processes, including erythrocyte differentiation; inner ear morphogenesis; and pharyngeal system development. Predicted to be located in basement membrane and extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranium; hematopoietic system; pectoral fin; pectoral fin bud; and vestibuloauditory system. Human ortholog(s) of this gene implicated in cervix carcinoma; endometrial carcinoma; multiple myeloma; and osteogenesis imperfecta type 17. Orthologous to human SPARC (secreted protein acidic and cysteine rich). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • SPARC
  • osn
  • osteonectin
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Properties