Protein Name MAD2 mitotic arrest deficient-like 1
Organism Mus musculus
Gene ID 56150
Gene Symbol

Mad2l1

UniProt Q9Z1B5 (MD2L1_MOUSE), Q5HZH8 (Q5HZH8_MOUSE)
Relationships Total Number of functionally related compound(s) : 20
Total Number of Articles : 17
Description

MAD2 mitotic arrest deficient-like 1

Gene Summary

Predicted to enable protein homodimerization activity. Acts upstream of or within mitotic sister chromatid segregation and mitotic spindle assembly checkpoint signaling. Located in several cellular components, including kinetochore; nucleus; and spindle pole. Part of mitotic spindle assembly checkpoint MAD1-MAD2 complex. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • mitotic spindle assembly checkpoint protein MAD2A
  • MAD2 (mitotic arrest deficient, homolog)-like 1
  • MAD2-like protein 1
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Properties