Protein Name epoxide hydrolase 1
Organism Rattus norvegicus
Gene ID 25315
Gene Symbol

Ephx1

UniProt P07687 (HYEP_RAT)
Relationships Total Number of functionally related compound(s) : 153
Total Number of Articles : 84
Description

epoxide hydrolase 1

Gene Summary

Enables cis-stilbene-oxide hydrolase activity and enzyme binding activity. Involved in several processes, including cellular response to glucocorticoid stimulus; diol biosynthetic process; and liver development. Located in membrane. Biomarker of aflatoxins-related hepatocellular carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • epoxide hydrolase 1
  • epoxide hydratase
  • epoxide hydrolase 1 (microsomal xenobiotic hydrolase)
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Properties