Protein Name | epoxide hydrolase 1 |
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Organism | Rattus norvegicus |
Gene ID | 25315 |
Gene Symbol | Ephx1 |
UniProt | P07687 (HYEP_RAT) |
Relationships |
Total Number of functionally related compound(s) :
153
Total Number of Articles : 84 |
Description |
epoxide hydrolase 1 |
Gene Summary |
Enables cis-stilbene-oxide hydrolase activity and enzyme binding activity. Involved in several processes, including cellular response to glucocorticoid stimulus; diol biosynthetic process; and liver development. Located in membrane. Biomarker of aflatoxins-related hepatocellular carcinoma. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). [provided by Alliance of Genome Resources, Jun 2025] |
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