Protein Name Araf proto-oncogene, serine/threonine kinase
Organism Mus musculus
Gene ID 11836
Gene Symbol

Araf

UniProt P04627 (ARAF_MOUSE), Q8CAD1 (Q8CAD1_MOUSE)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 7
Description

Araf proto-oncogene, serine/threonine kinase

Gene Summary

Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in several processes, including MAPK cascade; regulation of TOR signaling; and regulation of protein metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and retina. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human ARAF (A-Raf proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • serine/threonine-protein kinase A-Raf
  • A-Raf proto-oncogene serine/threonine-protein kinase
  • proto-oncogene A-Raf
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Properties