Protein Name tRNA ligase
Organism Saccharomyces cerevisiae S288C
Gene ID 853358
Gene Symbol

TRL1

UniProt P09880 (TRNL_YEAST)
Relationships Total Number of functionally related compound(s) : 21
Total Number of Articles : 11
Description

tRNA ligase

Gene Summary

Enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; and RNA ligase (ATP) activity. Involved in IRE1-mediated unfolded protein response; regulation of gene expression; and tRNA splicing, via endonucleolytic cleavage and ligation. Acts upstream of or within nuclear-transcribed mRNA catabolic process, no-go decay. Located in cytoplasm and nuclear inner membrane. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tRNA ligase
  • YJL087C
  • LIG1
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Properties