| Protein Name | holocarboxylase synthetase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3141 |
| Gene Symbol | HLCS |
| UniProt | P50747 (BPL1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
189
Total Number of Articles : 195 |
Description |
holocarboxylase synthetase |
| Gene Summary |
This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011] |
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