Protein Name tissue factor pathway inhibitor 2
Organism Homo sapiens
Gene ID 7980
Gene Symbol

TFPI2

UniProt P48307 (TFPI2_HUMAN)
Relationships Total Number of functionally related compound(s) : 93
Total Number of Articles : 92
Description

tissue factor pathway inhibitor 2

Gene Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

synonyms
  • tissue factor pathway inhibitor 2
  • placental protein 5
  • retinal pigment epithelium cell factor 1
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Properties