| Protein Name | mitochondrial calcium uptake 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10367 |
| Gene Symbol | MICU1 |
| UniProt | Q9BPX6 (MICU1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
45
Total Number of Articles : 60 |
Description |
mitochondrial calcium uptake 1 |
| Gene Summary |
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013] |
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