| Protein Name | cholinergic receptor, muscarinic 1, CNS |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12669 |
| Gene Symbol | Chrm1 |
| UniProt | P12657 (ACM1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
68
Total Number of Articles : 44 |
Description |
cholinergic receptor, muscarinic 1, CNS |
| Gene Summary |
Predicted to enable G protein-coupled acetylcholine receptor activity. Involved in postsynaptic modulation of chemical synaptic transmission and regulation of postsynaptic membrane potential. Acts upstream of or within regulation of locomotion. Is active in Schaffer collateral - CA1 synapse; cholinergic synapse; and postsynaptic membrane. Is expressed in central nervous system; exocrine system; facial prominence; retina; and urinary system. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome; asthma; and myasthenia gravis. Orthologous to human CHRM1 (cholinergic receptor muscarinic 1). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |