Protein Name oxytocin receptor
Organism Rattus norvegicus
Gene ID 25342
Gene Symbol

Oxtr

UniProt P70536 (OXYR_RAT)
Relationships Total Number of functionally related compound(s) : 93
Total Number of Articles : 103
Description

oxytocin receptor

Gene Summary

Enables ionotropic glutamate receptor binding activity; oxytocin receptor activity; and peptide hormone binding activity. Involved in several processes, including ERK1 and ERK2 cascade; estrous cycle; and positive regulation of synaptic transmission. Located in adherens junction; apical plasma membrane; and microvillus. Used to study alcohol dependence and gastric ulcer. Biomarker of hypertension. Human ortholog(s) of this gene implicated in alcohol dependence; depressive disorder; impulse control disorder; personality disorder; and substance abuse (multiple). Orthologous to human OXTR (oxytocin receptor). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • oxytocin receptor
  • oxcytocin receptor
  • OT-R
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Properties