| Protein Name | phospholipase C, gamma 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25738 |
| Gene Symbol | Plcg1 |
| UniProt | P10686 (PLCG1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
126
Total Number of Articles : 159 |
Description |
phospholipase C, gamma 1 |
| Gene Summary |
Enables several functions, including guanyl-nucleotide exchange factor activity; insulin receptor binding activity; and phospholipase C activity. Involved in several processes, including inositol trisphosphate biosynthetic process; phosphatidylinositol catabolic process; and positive regulation of cell size. Located in clathrin-coated vesicle. Biomarker of acute myocardial infarction and colon cancer. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung non-small cell carcinoma. Orthologous to human PLCG1 (phospholipase C gamma 1). [provided by Alliance of Genome Resources, Jul 2025] |
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