Protein Name | serine peptidase inhibitor Kazal type 1 |
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Organism | Homo sapiens |
Gene ID | 6690 |
Gene Symbol | SPINK1 |
UniProt | P00995 (ISK1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
218
Total Number of Articles : 199 |
Description |
serine peptidase inhibitor Kazal type 1 |
Gene Summary |
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] |
synonyms |
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Properties | |