| Protein Name | ADP-ribosylation factor-like 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 56350 |
| Gene Symbol | Arl3 |
| UniProt | Q9WUL7 (ARL3_MOUSE), Q543P7 (Q543P7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 2 |
Description |
ADP-ribosylation factor-like 3 |
| Gene Summary |
Enables GTPase activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Involved in several processes, including Golgi to plasma membrane transport; photoreceptor cell development; and protein localization to ciliary membrane. Acts upstream of or within intraciliary transport and smoothened signaling pathway. Located in axoneme; ciliary basal body; and ciliary transition zone. Is expressed in central nervous system; retina nuclear layer; and skin. Used to study autosomal recessive polycystic kidney disease and retinitis pigmentosa 2. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa 83. Orthologous to human ARL3 (ARF like GTPase 3). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |