| Protein Name | DNA topoisomerase I alpha |
|---|---|
| Organism | Arabidopsis thaliana |
| Gene ID | 835623 |
| Gene Symbol | TOP1ALPHA |
| UniProt | P30181 (TOP1A_ARATH), A0A654GB41 (A0A654GB41_ARATH), F4K3F4 (F4K3F4_ARATH), F4K3F5 (F4K3F5_ARATH) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 4 |
Description |
DNA topoisomerase I alpha |
| Gene Summary |
Encodes a type-I DNA topoisomerase I. Disruptions in this gene affect phyllotaxis and plant architecture suggesting that the gene plays a critical role in the maintenance of a regular pattern of organ initiation. Isolated as a protein oxidized during seed germination; proteomics approach revealed differences in de novo synthesis levels of this protein in condition with vs. without salicylic acid in the period from 0 to 40 hrs. following seed imbibition. Functions in stem cell maintenance at all stages of shoot and floral meristems and in the regulation of gene silencing. |
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