| Protein Name | aminolevulinate dehydratase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25374 |
| Gene Symbol | Alad |
| UniProt | P06214 (HEM2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
111
Total Number of Articles : 140 |
Description |
aminolevulinate dehydratase |
| Gene Summary |
Enables porphobilinogen synthase activity and proteasome core complex binding activity. Involved in several processes, including cellular response to lead ion; response to herbicide; and response to vitamin B1. Located in extracellular space. Used to study anemia and hemochromatosis. Biomarker of acute kidney failure; hypothyroidism; liver cirrhosis; and status epilepticus. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Jun 2025] |
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