| Protein Name | thyroid hormone receptor, beta L homeolog |
|---|---|
| Organism | Xenopus laevis |
| Gene ID | 779054 |
| Gene Symbol | thrb.L |
| UniProt | P18117 (THBA_XENLA), A0A1L8FWC5 (A0A1L8FWC5_XENLA) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 4 |
Description |
thyroid hormone receptor, beta L homeolog |
| Gene Summary |
Enables protein heterodimerization activity; sequence-specific DNA binding activity; and thyroid hormone binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in dermal system; mesoderm; musculoskeletal system; nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; prostate cancer; renal cell carcinoma; selective pituitary thyroid hormone resistance; and thyroid hormone resistance syndrome. Orthologous to human THRB (thyroid hormone receptor beta). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |