Protein Name phosphodiesterase 8B
Organism Mus musculus
Gene ID 218461
Gene Symbol

Pde8b

UniProt E9PYP0 (E9PYP0_MOUSE), E9PX38 (E9PX38_MOUSE), E9Q8J6 (E9Q8J6_MOUSE), Q8BI47 (Q8BI47_MOUSE), E9PXX4 (E9PXX4_MOUSE)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 7
Description

phosphodiesterase 8B

Gene Summary

Enables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including behavioral fear response; learning; and negative regulation of steroid hormone biosynthetic process. Is expressed in several structures, including alimentary system; central nervous system; hindlimb digit; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease 3. Orthologous to human PDE8B (phosphodiesterase 8B). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • cell proliferation-inducing gene 22 protein
  • B230331L10Rik
Click to show/hide the synonyms
Properties