Protein Name retromer subunit VPS35
Organism Saccharomyces cerevisiae S288C
Gene ID 853287
Gene Symbol

VPS35

UniProt P34110 (VPS35_YEAST)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 3
Description

retromer subunit VPS35

Gene Summary

Contributes to cargo adaptor activity. Involved in protein retention in Golgi apparatus and retrograde transport, endosome to Golgi. Located in endosome and fungal-type vacuole membrane. Part of retromer, cargo-selective complex. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • retromer subunit VPS35
  • YJL154C
  • ENV1
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Properties