Protein Name nuclear factor I/B
Organism Mus musculus
Gene ID 18028
Gene Symbol

Nfib

UniProt P97863 (NFIB_MOUSE), Q6GSP7 (Q6GSP7_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 4
Description

nuclear factor I/B

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including lung epithelial cell differentiation; negative regulation of cell population proliferation; and nervous system development. Acts upstream of or within several processes, including exit from mitosis; nervous system development; and salivary gland development. Located in cerebellar mossy fiber and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and respiratory system. Orthologous to human NFIB (nuclear factor I B). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • nuclear factor 1 B-type
  • CCAAT-box-binding transcription factor
  • TGGCA-binding protein
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Properties