Protein Name quinoid dihydropteridine reductase
Organism Rattus norvegicus
Gene ID 64192
Gene Symbol

Qdpr

UniProt P11348 (DHPR_RAT)
Relationships Total Number of functionally related compound(s) : 55
Total Number of Articles : 34
Description

quinoid dihydropteridine reductase

Gene Summary

Enables 6,7-dihydropteridine reductase activity; adenyl nucleotide binding activity; and identical protein binding activity. Involved in several processes, including L-phenylalanine catabolic process; response to glucagon; and tetrahydrobiopterin biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Biomarker of hypertension and status epilepticus. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia C and phenylketonuria. Orthologous to human QDPR (quinoid dihydropteridine reductase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • dihydropteridine reductase
  • HDHPR
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Properties