| Protein Name | roundabout 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 37603 |
| Gene Symbol | robo1 |
| UniProt | Q9W213 (Q9W213_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 10 |
Description |
roundabout 1 |
| Gene Summary |
Enables heparin binding activity. Involved in several processes, including animal organ development; neuron projection guidance; and regulation of cell migration. Located in several cellular components, including axonal growth cone; dendrite; and neuronal cell body. Part of Slit-Robo signaling complex. Is expressed in several structures, including cardioblast; central nervous system; epithelium; extended germ band embryo; and sensory neurons. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to several human genes including ROBO1 (roundabout guidance receptor 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |