Protein Name arylsulfatase B
Organism Homo sapiens
Gene ID 411
Gene Symbol


UniProt P15848 (ARSB_HUMAN), A0A024RAJ9 (A0A024RAJ9_HUMAN), A8K4A0 (A8K4A0_HUMAN)
Relationships Total Number of functionally related compound(s) : 192
Total Number of Articles : 188

arylsulfatase B

Gene Summary

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2016]

  • arylsulfatase B
  • N-acetylgalactosamine-4-sulfatase
  • ASB
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