| Protein Name | presenilin 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 81751 |
| Gene Symbol | Psen2 |
| UniProt | O88777 (PSN2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
16
Total Number of Articles : 11 |
Description |
presenilin 2 |
| Gene Summary |
Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Involved in response to hypoxia. Located in early endosome; synaptic membrane; and synaptic vesicle. Is active in presynaptic membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; Alzheimer's disease 4; breast cancer; and dilated cardiomyopathy 1V. Orthologous to human PSEN2 (presenilin 2). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
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| Properties | |