| Protein Name | natural cytotoxicity triggering receptor 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 259197 |
| Gene Symbol | NCR3 |
| UniProt | O14931 (NCTR3_HUMAN), Q05D23 (Q05D23_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
92
Total Number of Articles : 80 |
Description |
natural cytotoxicity triggering receptor 3 |
| Gene Summary |
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] |
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