| Protein Name | serum response factor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20807 |
| Gene Symbol | Srf |
| UniProt | Q9JM73 (SRF_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
91
Total Number of Articles : 94 |
Description |
serum response factor |
| Gene Summary |
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and primary miRNA binding activity. Involved in actin cytoskeleton organization; cardiac muscle cell myoblast differentiation; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including circulatory system development; hemopoiesis; and respiratory system development. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; embryo mesenchyme; future forebrain; and genitourinary system. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in cardiomyopathy and lymphangioleiomyomatosis. Orthologous to human SRF (serum response factor). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |