| Protein Name | hypoxanthine phosphoribosyltransferase 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24465 |
| Gene Symbol | Hprt1 |
| UniProt | P27605 (HPRT_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
70
Total Number of Articles : 61 |
Description |
hypoxanthine phosphoribosyltransferase 1 |
| Gene Summary |
Enables hypoxanthine phosphoribosyltransferase activity. Involved in cellular response to insulin stimulus; hypoxanthine metabolic process; and spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in HRPT-related hyperuricemia and Lesch-Nyhan syndrome. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025] |
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