Protein Name | NEDD4 E3 ubiquitin protein ligase |
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Organism | Rattus norvegicus |
Gene ID | 25489 |
Gene Symbol | Nedd4 |
UniProt | Q62940 (NEDD4_RAT), A0A0G2K8P3 (A0A0G2K8P3_RAT) |
Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 10 |
Description |
NEDD4 E3 ubiquitin protein ligase |
Gene Summary |
Enables ubiquitin-protein transferase activity. Involved in several processes, including protein K63-linked ubiquitination; regulation of postsynaptic neurotransmitter receptor internalization; and regulation of protein catabolic process at postsynapse, modulating synaptic transmission. Located in microvillus. Is active in glutamatergic synapse. Biomarker of muscular atrophy. Orthologous to human NEDD4 (NEDD4 E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |