Protein Name tRNA methyltransferase 5
Organism Homo sapiens
Gene ID 57570
Gene Symbol

TRMT5

UniProt Q32P41 (TRM5_HUMAN)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 11
Description

tRNA methyltransferase 5

Gene Summary

tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]

synonyms
  • tRNA (guanine(37)-N1)-methyltransferase
  • M1G-methyltransferase
  • TRM5 tRNA methyltransferase 5 homolog
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Properties