Protein Name eukaryotic translation initiation factor 2B subunit delta
Organism Homo sapiens
Gene ID 8890
Gene Symbol

EIF2B4

UniProt Q9UI10 (EI2BD_HUMAN), F8W8L6 (F8W8L6_HUMAN), E7ERK9 (E7ERK9_HUMAN), Q9HBP7 (Q9HBP7_HUMAN), Q71US4 (Q71US4_HUMAN), B4DUP5 (B4DUP5_HUMAN)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 59
Description

eukaryotic translation initiation factor 2B subunit delta

Gene Summary

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • translation initiation factor eIF2B subunit delta
  • eIF-2B GDP-GTP exchange factor subunit delta
  • eIF2B GDP-GTP exchange factor subunit delta
Click to show/hide the synonyms
Properties