Protein Name | eukaryotic translation initiation factor 2B subunit delta |
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Organism | Homo sapiens |
Gene ID | 8890 |
Gene Symbol | EIF2B4 |
UniProt | Q9UI10 (EI2BD_HUMAN), F8W8L6 (F8W8L6_HUMAN), E7ERK9 (E7ERK9_HUMAN), Q9HBP7 (Q9HBP7_HUMAN), Q71US4 (Q71US4_HUMAN), B4DUP5 (B4DUP5_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 59 |
Description |
eukaryotic translation initiation factor 2B subunit delta |
Gene Summary |
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |