Protein Name azurocidin 1
Organism Homo sapiens
Gene ID 566
Gene Symbol


UniProt P20160 (CAP7_HUMAN)
Relationships Total Number of functionally related compound(s) : 124
Total Number of Articles : 103

azurocidin 1

Gene Summary

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]

  • azurocidin
  • cationic antimicrobial protein 37
  • cationic antimicrobial protein CAP37
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