Protein Name N-deacetylase and N-sulfotransferase 1
Organism Rattus norvegicus
Gene ID 29633
Gene Symbol

Ndst1

UniProt Q02353 (NDST1_RAT)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 7
Description

N-deacetylase and N-sulfotransferase 1

Gene Summary

Enables [heparan sulfate]-glucosamine N-sulfotransferase activity and heparan sulfate N-deacetylase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
  • Golgi heparan sulfate N-deacetylase/N-sulfotransferase
  • HSNST 1
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Properties