Protein Name FKBP prolyl isomerase 2
Organism Homo sapiens
Gene ID 2286
Gene Symbol

FKBP2

UniProt P26885 (FKBP2_HUMAN), Q53XJ5 (Q53XJ5_HUMAN)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 15
Description

FKBP prolyl isomerase 2

Gene Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

synonyms
  • peptidyl-prolyl cis-trans isomerase FKBP2
  • 13 kDa FK506-binding protein
  • 13 kDa FKBP
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Properties