Protein Name | FKBP prolyl isomerase 2 |
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Organism | Homo sapiens |
Gene ID | 2286 |
Gene Symbol | FKBP2 |
UniProt | P26885 (FKBP2_HUMAN), Q53XJ5 (Q53XJ5_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
19
Total Number of Articles : 15 |
Description |
FKBP prolyl isomerase 2 |
Gene Summary |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
synonyms |
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Properties | |