Protein Name PH domain-containing protein
Organism Caenorhabditis elegans
Gene ID 173986
Gene Symbol

tbc-2

UniProt Q23419 (Q23419_CAEEL)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 2
Description

PH domain-containing protein

Gene Summary

Enables GTPase activator activity. Involved in positive regulation of early endosome to late endosome transport and regulation of presynaptic dense core granule exocytosis. Located in cholinergic synapse and late endosome. Is expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Orthologous to several human genes including TBC1D2 (TBC1 domain family member 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • PH domain-containing protein
  • CELE_ZK1248.10
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Properties