Protein Name Phosphocholine cytidylyltransferase 1
Organism Drosophila melanogaster
Gene ID 117353
Gene Symbol

Pcyt1

UniProt Q7K4C7 (Q7K4C7_DROME)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 5
Description

Phosphocholine cytidylyltransferase 1

Gene Summary

Enables choline-phosphate cytidylyltransferase activity. Involved in several processes, including determination of adult lifespan; establishment of ommatidial planar polarity; and imaginal disc-derived wing morphogenesis. Located in nucleus. Is expressed in several structures, including adult head; amnioserosa primordium; anterior endoderm; embryonic/larval midgut primordium; and epithelium. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy and spondylometaphyseal dysplasia with cone-rod dystrophy. Orthologous to human PCYT1A (phosphate cytidylyltransferase 1A, choline). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • phosphocholine cytidylyltransferase 1
  • CG1049-PA
  • CG1049-PB
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Properties