Protein Name keratin 19
Organism Homo sapiens
Gene ID 3880
Gene Symbol

KRT19

UniProt P08727 (K1C19_HUMAN)
Relationships Total Number of functionally related compound(s) : 189
Total Number of Articles : 188
Description

keratin 19

Gene Summary

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]

synonyms
  • keratin, type I cytoskeletal 19
  • 40-kDa keratin intermediate filament
  • CK-19
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Properties