Protein Name bradykinin receptor B2
Organism Homo sapiens
Gene ID 624
Gene Symbol

BDKRB2

UniProt P30411 (BKRB2_HUMAN)
Relationships Total Number of functionally related compound(s) : 220
Total Number of Articles : 216
Description

bradykinin receptor B2

Gene Summary

This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]

synonyms
  • B2 bradykinin receptor
  • BK-2 receptor
  • B2R
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Properties