Protein Name sphingomyelin phosphodiesterase acid like 3A
Organism Homo sapiens
Gene ID 10924
Gene Symbol

SMPDL3A

UniProt Q92484 (ASM3A_HUMAN)
Relationships Total Number of functionally related compound(s) : 18
Total Number of Articles : 5
Description

sphingomyelin phosphodiesterase acid like 3A

Gene Summary

Enables phosphoric diester hydrolase activity and zinc ion binding activity. Involved in negative regulation of cGAS/STING signaling pathway and nucleoside triphosphate catabolic process. Located in extracellular exosome. Is active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cyclic GMP-AMP phosphodiesterase SMPDL3A
  • 0610010C24Rik
  • 2',3'-cGAMP phosphodiesterase SMPDL3A
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Properties