| Protein Name | trans-acting transcription factor 4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20688 |
| Gene Symbol | Sp4 |
| UniProt | Q6DFV2 (Q6DFV2_MOUSE), A0A1Y7VJR5 (A0A1Y7VJR5_MOUSE), K4DI62 (K4DI62_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
17
Total Number of Articles : 16 |
Description |
trans-acting transcription factor 4 |
| Gene Summary |
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Jun 2025] |
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