Protein Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Organism Homo sapiens
Gene ID 116988
Gene Symbol

AGAP3

UniProt Q96P47 (AGAP3_HUMAN), D3DX07 (D3DX07_HUMAN), Q86XV5 (Q86XV5_HUMAN), E7ESL9 (E7ESL9_HUMAN), C9J975 (C9J975_HUMAN), Q86ST5 (Q86ST5_HUMAN)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 6
Description

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

Gene Summary

This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. [provided by RefSeq, Apr 2017]

synonyms
  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3
  • CRAM-associated GTPase
  • CRMP (collapsin response mediator protein) associated
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Properties