Protein Name hydroxyacylglutathione hydrolase GLO4
Organism Saccharomyces cerevisiae S288C
Gene ID 854205
Gene Symbol

GLO4

UniProt Q12320 (GLO4_YEAST)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 3
Description

hydroxyacylglutathione hydrolase GLO4

Gene Summary

Enables hydroxyacylglutathione hydrolase activity. Involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in paroxysmal nonkinesigenic dyskinesia 1. Orthologous to several human genes including HAGH (hydroxyacylglutathione hydrolase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • hydroxyacylglutathione hydrolase GLO4
  • YOR040W
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Properties