Protein Name S100 calcium binding protein B
Organism Rattus norvegicus
Gene ID 25742
Gene Symbol

S100b

UniProt P04631 (S100B_RAT)
Relationships Total Number of functionally related compound(s) : 194
Total Number of Articles : 218
Description

S100 calcium binding protein B

Gene Summary

Enables RAGE receptor binding activity; identical protein binding activity; and metal ion binding activity. Involved in several processes, including long-term synaptic potentiation; positive regulation of myelination; and response to anesthetic. Located in extracellular space. Used to study demyelinating disease. Biomarker of several diseases, including bipolar disorder; borna disease; brain edema; cerebrovascular disease (multiple); and depressive disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein S100-B
  • S-100 protein beta chain
  • S-100 protein subunit beta
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Properties