Protein Name MER proto-oncogene, tyrosine kinase
Organism Homo sapiens
Gene ID 10461
Gene Symbol

MERTK

UniProt Q12866 (MERTK_HUMAN)
Relationships Total Number of functionally related compound(s) : 111
Total Number of Articles : 118
Description

MER proto-oncogene, tyrosine kinase

Gene Summary

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]

synonyms
  • tyrosine-protein kinase Mer
  • MER receptor tyrosine kinase
  • STK kinase
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Properties