Protein Name glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Organism Mus musculus
Gene ID 14447
Gene Symbol

Gapdhs

UniProt Q64467 (G3PT_MOUSE), A0A0R4J0X7 (A0A0R4J0X7_MOUSE), S4R2G5 (S4R2G5_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 7
Description

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Gene Summary

Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Is expressed in cerebral cortex; heart; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glyceraldehyde-3-phosphate dehydrogenase, testis-specific
  • GAPDH-2
  • spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2
Click to show/hide the synonyms
Properties